It is rare in clinical practice to encounter complete heart block co-occuring with tachyarrhythmias. We are hereby presenting such a case which on workup turned out to be a channelopathy.
View AbstractWolfram syndrome (WS) is a rare neurodegenerative and genetic disorder, also known by the synonym DIDMOAD, which stands for diabetes insipidus (DI), childhood-onset diabetes mellitus (DM), optic atrophy (OA), and deafness (D).
View AbstractThe case is about a young male with right ventricular arrhythmogenic cardiomyopathy.
View AbstractCardiovascular disease (CVD) is the largest cause of mortality worldwide, with CAD being the most frequent type caused by atherosclerosis. Genetic factors are responsible for 40-60% of CAD vulnerability. MiRNAs show potential as biomarkers since they regulate important pathways in CAD.
View AbstractIn people with diabetes mellitus, the presence of myocardial dysfunction in the absence of overt clinical coronary artery disease, valvular disease, and other conventional cardiovascular risk factors, such as hypertension and dyslipidemia, has led to the descriptive terminology, diabetic cardiomyopathy.
View AbstractMisoprostol , a synthetic prostaglandin E1 (PGE1) analogue is routinely used to induce abortion . Cardiopulmonary complications have been previously reported with the use of prostaglandin analogues but not with misoprostol.
View AbstractDiabetes is a chronic, metabolic disease characterized by increased blood glucose levels, the most common is type 2 diabetes. Diabetes risk-screening tools are validated and implemented across various countries.
View AbstractI am presenting an interesting case report of a 45 year old woman who presented to the emergency department with complaints of acute onset of breathlessness shortly after a stressful event.
View AbstractSpontaneous coronary artery dissection (SCAD), as a medical emergency, represents one of the non-atherosclerotic causes of an acute coronary syndrome (ACS).
View AbstractPRES (Post Reversible Encephalopathy Syndrome) is a clinical-radiological syndrome characterised by headache, seizure, altered mental status and visual loss and characterised by white matter vasogenic oedema affecting the posterior occipital and parietal lobes of the brain predominantly.
View AbstractPoPH (portopulmonary hypertension) is being increasingly recognized as an important cause of PAH despite lacking precise diagnostic and treatment modalities
View AbstractThe prevalence of hypertension in India is estimated to be at least 25%, of which secondary hypertension accounts for 1.1 to 5.7% cases. Pheochromocytoma is one of the endocrine causes of secondary hypertension which is seen in less than 1% of patients.
View AbstractWernicke's encephalopathy (WE) is a frequently overlooked condition resulting from a deficiency of thiamine. Wernicke’s encephalopathy that results as a consequence of hyperemesis in pregnant.
View AbstractChronic kidney disease (CKD) is a progressive renal disorder characterized by a glomerular filtrate rate (GFR) of less than 60 ml/min/1.73m2 for three months or more.
View AbstractHLH is a syndrome of excessive immune activation leading to widespread inflammation and tissue destruction.Although few cases of HLH secondary to Salmonella Typhi have been reported,those caused by Salmonella Paratyphi are scarce.
View AbstractCalcium is essential for intracellular signalling for secretion of hormones, muscle contraction and coagulation cascade. • This study is to find the prevalence, etiology of hypocalcaemia in hospitalised patients in a tertiary care centre.
View AbstractFungal infective endocarditis is a relatively uncommon form of endocarditis accounting for only 1.3% to 6% of all cases of infectious endocarditis and requires a higher index of suspicion especially in patients who have undergone a prosthetic valve placement surgery.
View AbstractFew diseases present greater difficulty in the way of diagnosis than cure, Infective endocarditis being one of them, the hurdles are insurmountable in practice. A bacterial or fungal infection of valvular or endocardial surface of heart.
View AbstractCardiovascular disease remains one of the leading cause of mortality and morbidity in India .Identification of ST elevation myocardial infarction (STEMI) is critical because early reperfusion can save myocardium and increase survival.
View AbstractDiabetic Kidney Disease (DKD) is one of the primary cause of End stage renal disease(ESRD). Early diagnosis is very important in preventing the development of Diabetic nephropthy.
View AbstractFamilial hyperlipidemias can present with simple manifestations like gall stones to life threatening events like myocardial infarction,CVA or severe acute pancreatitis.It is hence important to identify these at the earliest and start appropriate medications to avoid future catastrophe.Here are some of the cases encountered in our practice.
View AbstractVericiguat is a novel oral Soluble Guanylate Cyclase (sGC) Stimulator . On stimulation it leads to a signaling cascade whichconverts guanosine triphosphate (GTP) to cyclic guanosine monophosphate (cGMP).
View Abstract